The Webb City girls turned back Nixa in girls COC Large Division hoops action.
With the Cardinals leading 23-16 at the half, the Eagles went on a 22-12 tear through the third quarter to stake a 38-35 lead starting the fourth.
Kambrey Cooper then stepped up with two key 3-pointers, her only two of the game, in the fourth for the Cardinals and helped push them to victory.
After three games in three days — including an overtime battle with Nevada on Tuesday — Cardinals coach Brad Shorter said his team was running on fumes.
Mikaela Burgess led the Cardinals with 24 points.